Understanding and Managing Tardive Dyskinesia: Treatment Options and Approaches

Tardive dyskinesia (TD) is a challenging neurological condition characterized by involuntary, repetitive movements, typically affecting the face, mouth, and other body parts. This condition often develops as a side effect of long-term use of certain medications, particularly antipsychotics. Understanding the available treatment options is crucial for individuals seeking relief from TD symptoms and improved quality of life.

Understanding and Managing Tardive Dyskinesia: Treatment Options and Approaches

FDA-Approved Medications for Tardive Dyskinesia

Two medications specifically approved by the FDA for treating tardive dyskinesia are vesicular monoamine transporter 2 (VMAT2) inhibitors: valbenazine and deutetrabenazine. These medications work by regulating dopamine levels in the brain, helping to reduce involuntary movements. Clinical trials have shown significant improvement in TD symptoms for many patients using these medications.

Alternative Treatment Approaches

Beyond FDA-approved medications, several alternative approaches may help manage TD symptoms. These include:

  • Adjusting or gradually discontinuing the causative medication (under medical supervision)

  • Natural supplements like vitamin E and ginkgo biloba

  • Behavioral therapy and relaxation techniques

  • Deep brain stimulation in severe cases

Treatment Costs and Insurance Coverage


Treatment Option Average Monthly Cost Typical Insurance Coverage
Valbenazine $6,000-$8,000 Often covered with prior authorization
Deutetrabenazine $5,000-$7,000 Usually covered with prerequisites
Vitamin E Therapy $20-$50 Generally not covered
Deep Brain Stimulation $40,000-$100,000 (procedure) Varies by insurance plan

Prices, rates, or cost estimates mentioned in this article are based on the latest available information but may change over time. Independent research is advised before making financial decisions.


Prevention and Early Intervention

Early recognition and intervention are vital in managing tardive dyskinesia. Regular monitoring for early signs of TD in patients taking antipsychotic medications can help healthcare providers adjust treatment plans before symptoms become severe. Preventive strategies may include using the lowest effective dose of antipsychotic medications and regular neurological examinations.

Working with Healthcare Providers

Successfully managing tardive dyskinesia requires close collaboration with healthcare providers. Treatment plans should be individualized, considering factors such as:

  • Severity of symptoms

  • Underlying medical conditions

  • Current medications

  • Patient preferences and lifestyle

  • Cost considerations and insurance coverage

The journey to managing tardive dyskinesia effectively often involves trying different treatment approaches and maintaining open communication with healthcare providers to find the most suitable combination of interventions for each individual’s specific situation.

This article is for informational purposes only and should not be considered medical advice. Please consult a qualified healthcare professional for personalized guidance and treatment.